Ibotenic Acid Biosynthesis in the Fly Agaric Is Initiated by Glutamate Hydroxylation
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چکیده
منابع مشابه
Pigments of fly agaric (Amanita muscaria).
The complex pigment pattern of fly agaric (Amanita muscaria) cap skins has been studied by LC-DAD and mass spectrometry. Among the betaxanthins the corresponding derivatives of serine, threonine, ethanolamine, alanine, Dopa, phenylalanine and tryptophan are reported for the first time to contribute to the pigment pattern of fly agarics. Betalamic acid, the chromophoric precursor of betaxanthins...
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The naturally occurring heterocyclic amino acid ibotenic acid (Ibo) and the synthetic analogue thioibotenic acid (Thio-Ibo) possess interesting but dissimilar pharmacological activity at ionotropic and metabotropic glutamate receptors (iGluRs and mGluRs). Therefore, a series of Thio-Ibo analogues was synthesized. The synthesis included introduction of substituents by Suzuki and Grignard reactio...
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The concentrations of some trace elements (such as Fe, Ag, Zn, Mn, Cu, Cd, Mg, Ca, Na, K) were determined in the fruiting bodies of Fly Agaric Amanita muscaria (L.: Fr.) Pers. The mushrooms were collected in Poland in 1999 and 2000. The samples of dried and pulverized mushrooms (separately the caps and the stalks) were wet digested with concentrated nitric acid in PTFE vessels under pressure in...
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ژورنال
عنوان ژورنال: Angewandte Chemie International Edition
سال: 2020
ISSN: 1433-7851,1521-3773
DOI: 10.1002/anie.202001870